Hong Kong University of Science and Technology discovered a new mechanism of brain disease
September 2, 2016 Source: Hualong Net
Window._bd_share_config={ "common":{ "bdSnsKey":{ },"bdText":"","bdMini":"2","bdMiniList":false,"bdPic":"","bdStyle":" 0","bdSize":"16"},"share":{ }};with(document)0[(getElementsByTagName('head')[0]||body).appendChild(createElement('script')) .src='http://bdimg.share.baidu.com/static/api/js/share.js?v=89860593.js?cdnversion='+~(-new Date()/36e5)];Hong Kong, August 31st, a study published by the Hong Kong University of Science and Technology on the 31st found that new mechanisms leading to mental illness such as autism, mental retardation and schizophrenia will help to develop new therapies for these diseases in the future.
The research team led by Zhang Mingjie, a professor of Kerry Science at the Department of Life Sciences at the University of Science and Technology, found that the two major protein molecules, SynGAP and PSD-95, which are responsible for receiving the "post-synaptic dense region" of neural signals, can be assembled into a protein network structure. This structure will form stable "oil droplet" droplets. The study also found that defective proteins in the brain of autistic patients alter the composition of "oil droplets" of droplets, thereby altering the signal activity of neuronal synapses.
The researchers said the findings could explain the causes of autism and help understand why genetic mutations alter the interaction of these proteins, leading to a series of central nervous system diseases that have not been treated in a way that can be injected into research and development. New inspiration. It is understood that other neuropsychiatric diseases, including schizophrenia, mental retardation and depression, have the same formation mechanism. The research results have been published in the scientific journal Cell, published on August 25.
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