1. Pretreatment of raw materials (1) Before using the raw materials, check the product name, specification, quantity, number of pieces and test qualification list, and check the quality and sifting, and beware of foreign matter. (2) The raw and auxiliary materials after processing are placed in a clean and dry container, and labels are attached inside and outside, and records are made and transferred to the next process.
2. Ingredients and granulation (1) Check the label of the powder and thick paste (extract) which were transferred in the previous process, and accept it without any error.
(2) When calculating and feeding ingredients, the operator and the reviewer are required to sign the production record.
(3) The variety that needs to be granulated after granulation. When granulating, the powder should be mixed evenly, and a certain proportion of thick paste or adhesive is gradually added. When a batch number is divided into several granulations, the particle size should be the same and the tightness should be consistent.
(4) For the technical conditions such as temperature, concentration and quantity of the particle mixture, the necessary technical parameters must be formulated according to the characteristics of the variety, and the operation must be strictly controlled. Pure water should be used when granulating with water.
(5) Weighing instruments should be calibrated before use and periodically checked.
3. Drying (1) Control the thickness and quantity of wet granules in the drying tray according to the stipulations. During the drying process, the material should be frequently turned over, and ventilated regularly. The drying temperature should be recorded regularly to prevent coking and control the granule moisture within the specified range.
(2) The uniformity of the oven temperature should be checked regularly.
(3) When using a fluidized bed to dry, the air used should be cleaned and dedusted. During the operation, the presence or absence of the material should be checked continuously to make it dry evenly.
4. In the whole grain (1) The permanent hopper of the granulator should be equipped with a permanent magnet to absorb the iron filings accidentally entering the granules.
(2) The aromatic materials are gradually added in the whole granulation process after being calculated according to the specified content, so as to be uniformly mixed. After the particles of the aromatic material are mixed, they should be stored in the container for more than four hours to facilitate uniform penetration.
(3) The mixed particles are packed in a clean container. Labels should be attached to both inside and outside the container, indicating the product name, batch number, batch quantity, number of pieces, date, and work number, and send them to the intermediate station in time.
(4) Specially toxic varieties should be produced in a closed room, and the operator should isolate the operation. The indoor should be equipped with a dust suction device, and the excluded dust should be treated centrally.
5. Packing (1) Check the product name, specification, batch number and quantity of the semi-finished hollow capsule before packing. It should be consistent with the test pass.
(2) Hollow capsules, semi-finished products and finished products should be placed in a constant temperature and humidity room, and the room temperature should be 18-28 °C; the relative humidity should be 45%-65%.
(3) Manual dispensing: The dosage of each board should be adjusted, weighed, reviewed and signed; the quality of the special person should be checked, and the acceptance of each board after passing the inspection should be determined. Both the receipt and the delivery shall be inspected and the problem shall be issued and repaired or exchanged in time.
(4) Machine packaging: The person in charge shall be responsible for the commissioning and maintenance of the equipment. Before installation, the equipment shall be tested and checked for the difference in the volume. Appearance, after the test is qualified, the machine can be turned on. After the start-up, the average load should be checked regularly and adjusted in time. Machines, unqualified capsules in the test installation should be reworked.
(5) Weighing instruments used for weighing and testing should be calibrated before use and periodically checked.
(6) Packed semi-finished products into clean and dry containers, sealed and stored to prevent moisture absorption. Labels should be attached inside and outside the container, indicating the name, batch number, specification, quantity, number of pieces, date, work number, and then transferred to the next Process or intermediate station.
6. Before the capsule is inspected and the sac is checked, the white powder on the outer wall of the capsule should be cleaned and the non-conforming product should be discarded. After cleaning the outer wall of the capsule, it is then polished according to the process requirements. Capsules with good visual inspection are placed in clean, dry containers, and the internal and external labels are attached to the intermediate station.
7. Packaging (1) Pretreatment of packaging materials 1 Glass bottles are washed with drinking water, washed with pure water, dried and cleaned, cleaned and stored. Storage time should not exceed three days, and should be rewashed after the specified time. 2 The plastic bottle cap is packed, the outer packaging of the cork should be tight, and the interior is clean and dry. 3 The cotton, paper and other inner packaging materials that are in direct contact with the drug should be cleaned and sterilized by appropriate methods, and dried and sealed after sterilization.
(2) When packaging in aluminum plastic, the heat sealing temperature should be strictly controlled. The printed characters on the aluminum foil should be carefully prevented from falling off or becoming blurred.
(3) The number of utensils should be checked and cleaned by a person.
(4) The product name, specification, batch number, etc. on the packaging label must be checked. After the packaging is completed, the number of labels, the utility number and the remaining number should be accurately counted. The remaining labels and scrap labels are handled by the label management method.
2. Ingredients and granulation (1) Check the label of the powder and thick paste (extract) which were transferred in the previous process, and accept it without any error.
(2) When calculating and feeding ingredients, the operator and the reviewer are required to sign the production record.
(3) The variety that needs to be granulated after granulation. When granulating, the powder should be mixed evenly, and a certain proportion of thick paste or adhesive is gradually added. When a batch number is divided into several granulations, the particle size should be the same and the tightness should be consistent.
(4) For the technical conditions such as temperature, concentration and quantity of the particle mixture, the necessary technical parameters must be formulated according to the characteristics of the variety, and the operation must be strictly controlled. Pure water should be used when granulating with water.
(5) Weighing instruments should be calibrated before use and periodically checked.
3. Drying (1) Control the thickness and quantity of wet granules in the drying tray according to the stipulations. During the drying process, the material should be frequently turned over, and ventilated regularly. The drying temperature should be recorded regularly to prevent coking and control the granule moisture within the specified range.
(2) The uniformity of the oven temperature should be checked regularly.
(3) When using a fluidized bed to dry, the air used should be cleaned and dedusted. During the operation, the presence or absence of the material should be checked continuously to make it dry evenly.
4. In the whole grain (1) The permanent hopper of the granulator should be equipped with a permanent magnet to absorb the iron filings accidentally entering the granules.
(2) The aromatic materials are gradually added in the whole granulation process after being calculated according to the specified content, so as to be uniformly mixed. After the particles of the aromatic material are mixed, they should be stored in the container for more than four hours to facilitate uniform penetration.
(3) The mixed particles are packed in a clean container. Labels should be attached to both inside and outside the container, indicating the product name, batch number, batch quantity, number of pieces, date, and work number, and send them to the intermediate station in time.
(4) Specially toxic varieties should be produced in a closed room, and the operator should isolate the operation. The indoor should be equipped with a dust suction device, and the excluded dust should be treated centrally.
5. Packing (1) Check the product name, specification, batch number and quantity of the semi-finished hollow capsule before packing. It should be consistent with the test pass.
(2) Hollow capsules, semi-finished products and finished products should be placed in a constant temperature and humidity room, and the room temperature should be 18-28 °C; the relative humidity should be 45%-65%.
(3) Manual dispensing: The dosage of each board should be adjusted, weighed, reviewed and signed; the quality of the special person should be checked, and the acceptance of each board after passing the inspection should be determined. Both the receipt and the delivery shall be inspected and the problem shall be issued and repaired or exchanged in time.
(4) Machine packaging: The person in charge shall be responsible for the commissioning and maintenance of the equipment. Before installation, the equipment shall be tested and checked for the difference in the volume. Appearance, after the test is qualified, the machine can be turned on. After the start-up, the average load should be checked regularly and adjusted in time. Machines, unqualified capsules in the test installation should be reworked.
(5) Weighing instruments used for weighing and testing should be calibrated before use and periodically checked.
(6) Packed semi-finished products into clean and dry containers, sealed and stored to prevent moisture absorption. Labels should be attached inside and outside the container, indicating the name, batch number, specification, quantity, number of pieces, date, work number, and then transferred to the next Process or intermediate station.
6. Before the capsule is inspected and the sac is checked, the white powder on the outer wall of the capsule should be cleaned and the non-conforming product should be discarded. After cleaning the outer wall of the capsule, it is then polished according to the process requirements. Capsules with good visual inspection are placed in clean, dry containers, and the internal and external labels are attached to the intermediate station.
7. Packaging (1) Pretreatment of packaging materials 1 Glass bottles are washed with drinking water, washed with pure water, dried and cleaned, cleaned and stored. Storage time should not exceed three days, and should be rewashed after the specified time. 2 The plastic bottle cap is packed, the outer packaging of the cork should be tight, and the interior is clean and dry. 3 The cotton, paper and other inner packaging materials that are in direct contact with the drug should be cleaned and sterilized by appropriate methods, and dried and sealed after sterilization.
(2) When packaging in aluminum plastic, the heat sealing temperature should be strictly controlled. The printed characters on the aluminum foil should be carefully prevented from falling off or becoming blurred.
(3) The number of utensils should be checked and cleaned by a person.
(4) The product name, specification, batch number, etc. on the packaging label must be checked. After the packaging is completed, the number of labels, the utility number and the remaining number should be accurately counted. The remaining labels and scrap labels are handled by the label management method.
ELASTIC BANDAGE
Structure and composition: It is woven by chemical fiber and yarn in plain weave.
Product performance: Non-toxic, medical usage and environmentally friendly, using special and unique technology, through multiple processes. So that the mesh and elasticity of the product are always uniform, and the permeability is good.
Model specifications: Plain weave. The specification width is 5CM / 7.5CM / 10CM / 12CM / 15CM / 20CM, and the length is any fixed length between 3-20M.
Packing: Each roll packed with OPP candy paper, the outer layer is 5-layer double corrugated kraft paper box.
Gauze Bandage,Medical Bandage,Elastic Bandage,Medical Elastic Bandages
Shaoxing Gangfeng Hospital Products Co.,Ltd. , https://www.gangfenggauze.com