Oxford Nanopore Technologies revealed that it is developing a nanopore sensor for smartphones for DNA sequencing and other applications. The company also introduced other new products in research and development. In addition, the company established a branch called Genome Foundry, focusing on the application of synthetic biology.
Developed a nanopore instrument SmidgIon for connecting smartphones
Clive Brown, the company's chief technology officer, revealed that the new nanopore instrument, called SmidgIon, is in the early stages of development and is expected to be available by the end of 2017. The product will also use core nanopore sensing technology for MinIon and PromethIon instruments, but the instrument will be smaller than MinIon, with 256 channels per flow cell that can be connected to a smartphone or other low-power instrument. For sensing DNA, RNA or protein.
According to the company, SmidgIon can be used in a wider range of areas, including pathogen monitoring in disease outbreaks, analysis of environmental samples or agricultural samples, and real-time species identification of wildlife or wood.
Other products under development
Brown, another product in the early stages of development, is called Project Zumbador, which combines nucleic acid extraction and library preparation of biological samples into one device and will be released in the third quarter.
The company is also developing kits for direct RNA sequencing on MinIon and PromethIon, which are expected to be available to developers in the next few months. According to the company, the product uses adapters and motor proteins to control RNA translocation and direct RNA into the nanopore. Oxford has used this method to sequence RNA from human rhinoviruses and has indicated that direct RNA sequencing can detect methylation modifications on RNA.
Another product, the VolTrax, is a sample preparation instrument that will be available in advance this fall to customers currently using the Oxford nanopore sequencing platform. According to the company, the first Volrax instrument will be attached to a small USB instrument and attached to the MioIon or PromethIon instrument.
Oxford Nanopore also plans to implement the local use of the MinKonw platform base recognition software shortly.
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