Small-Molecule Inhibitor API Dasatinib (CAS# 302962-49-8)

Model NO.: Pharmaceutical Grade
Product Name: Dasatinib
Model No.: Atc-132
Molecular Formula: C22h28cln7o3s
Molecular Weight: 488.01
Product Specifications: Pharmaceutical Grade
MOQ(Minimum Order Quantity): 10g
Origion: Hubei, China
Brand: Newbio Pharmtech
Market: Global
Trademark: Biocar
Transport Package: Aluminum Foil Bag or as Required
Specification: SGS/ CTI/ ITS
Origin: Wuhan, Hubei, China
HS Code: 8676530000
Model NO.: Pharmaceutical Grade
Product Name: Dasatinib
Model No.: Atc-132
Molecular Formula: C22h28cln7o3s
Molecular Weight: 488.01
Product Specifications: Pharmaceutical Grade
MOQ(Minimum Order Quantity): 10g
Origion: Hubei, China
Brand: Newbio Pharmtech
Market: Global
Trademark: Biocar
Transport Package: Aluminum Foil Bag or as Required
Specification: SGS/ CTI/ ITS
Origin: Wuhan, Hubei, China
HS Code: 8676530000
High Purity Small-Molecule Inhibitor API Dasatinib (CAS: 302962-49-8)
 
Chemical Information
Quick Details:
Product Name Dasatinib
Molecular Formula C22H26ClN7O2S
Molecular Weight 488.01
Storage 3years in -20ºC
Targets Abl     Src     c-Kit (WT)/c-Kit (D816V)
IC50 0.6 nM    0.8 nM  
IC50 79 nM/37 nM
Dosage Oral administration, 10 mg/kg, daily
Product Name: Dasatinib
Other Name:Dasatinib(BMS-354825);BMS-354825;N-[2-Chloro-6-methylphenyl]-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide;5-Thiazolecarboxamide, N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-;Dasatinib;N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide;N-(2-chloro-6-methylphenyl)-2-(6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamide;2-{6-[4-(2-HYDROXY-ETHYL)-PIPERAZIN-1-YL]-2-METHYL-PYRIMIDIN-4-YLAMINO}-THIAZOLE-5-CARBOXYLIC ACID (2-CHLORO-6-METHYL-PHENYL)-AMIDE
Model No.: ATC-132
CAS No.: 302962-49-8
Molecular Formula: C22H28ClN7O3S
Molecular Weight:488.01
Stability: N/A
Target:N/A
Appearance: Pale-Yellow Solid
Melting Point: 275-286°C
Purity: 99%+
Suitable People: ALl
Product Specifications: Pharmaceutical Grade 
Standard: Qualified
MOQ(Minimum Order Quantity): 10g
Payment: L/C, T/T, Western Union
Shipment: EMS, DHL, FedEx, TNT
Packing: Aluminium Foil Bag or as Required    
Brand: Biocar
Origion: Hubei,China  
Export Markets: Global   
         
Product Description
Dasatinib is a small-molecule inhibitor of both the Src and Bcr-Abl tyrosine kinases with IC50 values of 0.5 nM and 1 nM.  The oncogenic tyrosine kinase Bcr-Abl, plays a critical role in the pathogenesis of CML (chronic myelogenous leukemia). In most CML patients, the kinase domain of Bcr-Abl have mutations that interfere with binding to the first Abl kinase inhibitor, but Dasatinib bind more efficiently to these Abl kinase mutations and thus more effective than imatinib in inhibiting the proliferation cells with wild-type Bcr-Abl or Bcr-Abl mutants.
 
Dasatinib is a cancer drug prescribed as treatment for certain kinds of leukemia, such as chronic myelogenous leukemia and some types of acute lymphocytic leukemia. It is sometimes prescribed when patients can no longer benefit from other leukemia treatments or can no longer take other cancer drugs because of their side effects. This medication is a tyrosine kinase inhibitor. Dasatinib prohibits leukemia cells from growing by blocking the signals of tyrosine kinases, which are proteins that signal cells to grow and divide.
 
Applications/Usage
There was no significant difference in survival between the different treatment groups. The median survival of vehicle-treated animals was 131 days compared with 127 days and 130 days for animals treated with dasatinib from 6 weeks and 10 weeks of age, respectively. Analysis of tumor burden in the mice showed that all mice had invasive PDAC; however, the number of mice with metastases was reduced significantly in dasatinib-treated animals. The incidence of metastases was 61.1% in vehicle-treated animals compared with 26.7% in mice treated with dasatinib from 6 weeks and 23.1% in mice treated with dasatinib from 10 weeks.
 
1.A new, oral, small-molecule Tyrosine Kinase Inhibitor (TKI) for the treatment of CML. Antineoplastic
 
2.Dasatinib is a novel, potent and multi-targeted inhibitor that targets Abl, Src and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM, respectively.
 
 
====================================================
 
Our Advantages
1.High quality and competetive price
1)For  exported we can offer COA Certificate and official Invoice.
2)We are manufacturer with own lab and factory, can provide high quality products with factory price. 
3)Products purity is test by our quality department strictly before sending, and you can also ask the third testing organization come and inspect, such as (SGS/ CTI/ ITS), only after your confirmation will we send it out to you.
 
2.Fast and safe delivery:
1)Products can be sent out in 24 hours after payment. Tracking number available, fixed service person are 7X24h for you to contact.
2) Secure and discreet shipment. Various transportation methods for your choice, like DHL/UPS/TNT/FedEx/SF-express.
3)Customs pass and satisfied rate ?Y99%.
4)For hot sale products we have stock in there for transferring. 
 
3 We have clients throughout the world:
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire. 
2) Market feedback and goods feedback will be appreciated, meeting customers' requirement is our responsibility. 
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers. 
 
1.The parcels will be sent within 24 hours once the order is verified.
2.Packaging is fully in accordance with customer demand.
3.There will be discounts whether you are an old customer or not.
 
BioCar's Featured Products:
 
AZD9291 1421373-65-0
E7080 417716-92-8
Afatinib diMaleate 439081-18-2
XL184 S-MALATE 1140909-48-3
Crizotinib 877399-52-5
Axitinib 319460-85-0
WZ4002 1213269-23-8
Vandetanib 443913-73-3
Sunitinib 557795-19-4
Regorafenib 755037-03-7
Imatinib 152459-95-5
 
Delivery Time
About 7 days

====================================================
 
Contact Us
Tel: 86-027-86879876
Mobile: 86-15327198583
Fax: 86-27-87050469
Website: http://www.besteroid.com/
Online Store:http://biocar.en.made-in-china.com/
©Wuhan Biocar Bio-Pharm Co., Ltd.
 



Delivery:
1) Products can be sent out within 24 hours after payment. 
2) Secure and discreet shipment. 
3) Various methods for your choice, like DHL/TNT/FedEx/SF-express.
 

Commitment:
1. We are manufacturer with own factory and we sale this product at a best quality and low price.
2. This product is available in stock, please contact the sale for more details.
3. We have QA & QC department to guarantees the ex-factory product pass rate can reach 100%. 


====================================================
Contactct:
Telephone: +86-027-87002705
Mobile: +86-13638641831 +86-13277093700
 
 
FaceBook: https://www.facebook.com/newbiopharma/
Website:  http://www.newbiopharm.com/
Online Store: http://biocar.en.made-in-china.com/
©Wuhan Newbio Pharm-Tech Co., Ltd.


Newbio is a reliable supplier and looks for a long term business relationship!!!

High Purity Small-Molecule Inhibitor API Dasatinib (CAS: 302962-49-8)
 
Chemical Information
Quick Details:
Product Name Dasatinib
Molecular Formula C22H26ClN7O2S
Molecular Weight 488.01
Storage 3years in -20ºC
Targets Abl     Src     c-Kit (WT)/c-Kit (D816V)
IC50 0.6 nM    0.8 nM  
IC50 79 nM/37 nM
Dosage Oral administration, 10 mg/kg, daily
Product Name: Dasatinib
Other Name:Dasatinib(BMS-354825);BMS-354825;N-[2-Chloro-6-methylphenyl]-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide;5-Thiazolecarboxamide, N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-;Dasatinib;N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide;N-(2-chloro-6-methylphenyl)-2-(6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamide;2-{6-[4-(2-HYDROXY-ETHYL)-PIPERAZIN-1-YL]-2-METHYL-PYRIMIDIN-4-YLAMINO}-THIAZOLE-5-CARBOXYLIC ACID (2-CHLORO-6-METHYL-PHENYL)-AMIDE
Model No.: ATC-132
CAS No.: 302962-49-8
Molecular Formula: C22H28ClN7O3S
Molecular Weight:488.01
Stability: N/A
Target:N/A
Appearance: Pale-Yellow Solid
Melting Point: 275-286°C
Purity: 99%+
Suitable People: ALl
Product Specifications: Pharmaceutical Grade 
Standard: Qualified
MOQ(Minimum Order Quantity): 10g
Payment: L/C, T/T, Western Union
Shipment: EMS, DHL, FedEx, TNT
Packing: Aluminium Foil Bag or as Required    
Brand: Biocar
Origion: Hubei,China  
Export Markets: Global   
         
Product Description
Dasatinib is a small-molecule inhibitor of both the Src and Bcr-Abl tyrosine kinases with IC50 values of 0.5 nM and 1 nM.  The oncogenic tyrosine kinase Bcr-Abl, plays a critical role in the pathogenesis of CML (chronic myelogenous leukemia). In most CML patients, the kinase domain of Bcr-Abl have mutations that interfere with binding to the first Abl kinase inhibitor, but Dasatinib bind more efficiently to these Abl kinase mutations and thus more effective than imatinib in inhibiting the proliferation cells with wild-type Bcr-Abl or Bcr-Abl mutants.
 
Dasatinib is a cancer drug prescribed as treatment for certain kinds of leukemia, such as chronic myelogenous leukemia and some types of acute lymphocytic leukemia. It is sometimes prescribed when patients can no longer benefit from other leukemia treatments or can no longer take other cancer drugs because of their side effects. This medication is a tyrosine kinase inhibitor. Dasatinib prohibits leukemia cells from growing by blocking the signals of tyrosine kinases, which are proteins that signal cells to grow and divide.
 
Applications/Usage
There was no significant difference in survival between the different treatment groups. The median survival of vehicle-treated animals was 131 days compared with 127 days and 130 days for animals treated with dasatinib from 6 weeks and 10 weeks of age, respectively. Analysis of tumor burden in the mice showed that all mice had invasive PDAC; however, the number of mice with metastases was reduced significantly in dasatinib-treated animals. The incidence of metastases was 61.1% in vehicle-treated animals compared with 26.7% in mice treated with dasatinib from 6 weeks and 23.1% in mice treated with dasatinib from 10 weeks.
 
1.A new, oral, small-molecule Tyrosine Kinase Inhibitor (TKI) for the treatment of CML. Antineoplastic
 
2.Dasatinib is a novel, potent and multi-targeted inhibitor that targets Abl, Src and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM, respectively.
 
 
====================================================
 
Our Advantages
1.High quality and competetive price
1)For  exported we can offer COA Certificate and official Invoice.
2)We are manufacturer with own lab and factory, can provide high quality products with factory price. 
3)Products purity is test by our quality department strictly before sending, and you can also ask the third testing organization come and inspect, such as (SGS/ CTI/ ITS), only after your confirmation will we send it out to you.
 
2.Fast and safe delivery:
1)Products can be sent out in 24 hours after payment. Tracking number available, fixed service person are 7X24h for you to contact.
2) Secure and discreet shipment. Various transportation methods for your choice, like DHL/UPS/TNT/FedEx/SF-express.
3)Customs pass and satisfied rate ?Y99%.
4)For hot sale products we have stock in there for transferring. 
 
3 We have clients throughout the world:
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire. 
2) Market feedback and goods feedback will be appreciated, meeting customers' requirement is our responsibility. 
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers. 
 
1.The parcels will be sent within 24 hours once the order is verified.
2.Packaging is fully in accordance with customer demand.
3.There will be discounts whether you are an old customer or not.
 
BioCar's Featured Products:
 
AZD9291 1421373-65-0
E7080 417716-92-8
Afatinib diMaleate 439081-18-2
XL184 S-MALATE 1140909-48-3
Crizotinib 877399-52-5
Axitinib 319460-85-0
WZ4002 1213269-23-8
Vandetanib 443913-73-3
Sunitinib 557795-19-4
Regorafenib 755037-03-7
Imatinib 152459-95-5
 
Delivery Time
About 7 days

====================================================
 
Contact Us
Tel: 86-027-86879876
Mobile: 86-15327198583
Fax: 86-27-87050469
Website: http://www.besteroid.com/
Online Store:http://biocar.en.made-in-china.com/
©Wuhan Biocar Bio-Pharm Co., Ltd.
 



Delivery:
1) Products can be sent out within 24 hours after payment. 
2) Secure and discreet shipment. 
3) Various methods for your choice, like DHL/TNT/FedEx/SF-express.
 

Commitment:
1. We are manufacturer with own factory and we sale this product at a best quality and low price.
2. This product is available in stock, please contact the sale for more details.
3. We have QA & QC department to guarantees the ex-factory product pass rate can reach 100%. 


====================================================
Contactct:
Telephone: +86-027-87002705
Mobile: +86-13638641831 +86-13277093700
 
 
FaceBook: https://www.facebook.com/newbiopharma/
Website:  http://www.newbiopharm.com/
Online Store: http://biocar.en.made-in-china.com/
©Wuhan Newbio Pharm-Tech Co., Ltd.


Newbio is a reliable supplier and looks for a long term business relationship!!!

Hospital Medical Disposable Underpad Manufacturer


Underpad Detailed introduction:

Our underpad are widely used for hospital bed, infant bed, wheelchair, operating table

 etc., protect patients, the elder and infants against body fluids contamination.

 

size cover bottom bottom sticker SAP Pad weight piece/pack packs/bag bags/40HQ
45x60cm non woven PE film without 1.5g 35g/piece 10 10 2000
60x60cm non woven PE film without 2g 45g/piece 10 10 1650
60x90cm non woven PE film without 3g 50g/piece 10 10 1100
80x140cm non woven PE film without 4h 60g/piece 10 10 950

1) Underpad super absorbent layer:

fluff fiber mixed with highly absorbent polymers draw in and condense all moisture instantly and sufficiently, preventing from flowing back and leakage.


2) Non-woven surface,

soft and breathable underpad.


3) Underpad with fine vents

to prevent from flowing back and keeps the skin dry and comfortable.


4) Underpad with print design

.No matter in the tissue paper or the PE film,we can printpictures or wetness indicator as your request

 

Suitable length and width of underpad

Large size underpad is ideal for overnight use and very heavy incontinence and big surgical operation; Extra-large underpad cover the sleeping area for superior bed linen protection.

Prevent leakage; keep skin dry, hygiene and comfortable; Protect bed cleanliness and control

odor effectively, Our maximum underpad size can be made in 140x80cm now.


PRODUCTS SHOW:

women underpad

baby underpads


PRODUCTION AND SHIPPING


adult underpad



 


Adult Underpad

Adult Underpad,Adult Medical Underpad,Washable Underpad,Disposable Adult Underpad

Tianjin Jiao rou Sanitary product company , http://www.tjsanitary.com

Posted on