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Model NO.: 171596-29-5
Appearance: White Powder
Delivery Way: FedEx, TNT, DHL, EMS
Packing Way: Very Discreet Packages
Trademark: Shijingu
Transport Package: Foil Bags
Specification: USP pharm grade
Origin: China
HS Code: 1564984165
Model NO.: 171596-29-5
Appearance: White Powder
Delivery Way: FedEx, TNT, DHL, EMS
Packing Way: Very Discreet Packages
Trademark: Shijingu
Transport Package: Foil Bags
Specification: USP pharm grade
Origin: China
HS Code: 1564984165
Tadalafil Basic information
Drug for treatment of male erectile dysfunction disease Uses
Product Name: Tadalafil
Synonyms: TADALAFIL;IC 351;(6r,12ar)-6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione;TADALAFIL;Taladafil ;taladafil;(IC351)
CAS: 171596-29-5
MF: C22H19N3O4
MW: 389.4
EINECS: 200-835-2
Product Categories: Active Pharmaceutical Ingredients;Cnbio;Erectile Dysfunction;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Steroid and Hormone;Inhibitor;API;Tadalafil;NUCYNTA;Pyridines ,Halogenated Heterocycles
Mol File: 171596-29-5.mol
Tadalafil Chemical Properties
mp  298-300°C
storage temp.  Hygroscopic, -20?C Freezer, Under Inert Atmosphere
CAS DataBase Reference 171596-29-5(CAS DataBase Reference)
 
Safety Information
Hazard Codes  F,Xn
Risk Statements  11-20/21/22-36
Safety Statements  16-36/37
Hazardous Substances Data 171596-29-5(Hazardous Substances Data)
MSDS Information
 
Tadalafil Usage And Synthesis
Drug for treatment of male erectile dysfunction disease tadalafil, is an orally administrated drug developed by the pharmaceutical company Eli Lily for treatment of male erectile dysfunction disease. It belongs to the second generation of phosphodiesterase type 5 inhibitors. Study has shown that compared , the onset rate of tadalafil is very rapid with about 15 ~ 20 min for onset and with long-term effects up to 36h. Its T1/2 was 17.5h. In a study including 348 cases of patients with mild to severe erectile dysfunction, male patients were randomized for being subject to 20 mg of tadalafil or placebo. The results have showed that, compared with placebo, the intercourse success rate at 24 and 36 hours after taking the drug are both improved with most male patients can successfully have sexual intercourse for twice within 36 hours. There is also no difference in the incidence and severity of the adverse drug reactions compared with placebo. In the tadalafil group, more than 5% of men get headache and indigestion. 
[Adverse reactions] it has no serious adverse reactions. No adverse reactions such as facial flushing, vision abnormalities after serving have been observed. There has been occasionally headache and indigestion.
[Note] for patients serving nitrates, angina, heart disease, uncontrolled hypertension or hypotension. Patients who had got stroke within the past six months should be disabled.
The above information is edited by the chemicalbook of Dai Xiongfeng.
Uses It is a kind of PDE-5 inhibitors which can be used for the treatment of male erectile dysfunction. It is also the second generation of phosphodiesterase type 5 inhibitors used to treat male erectile dysfunction
Chemical Properties White to Off-White Cyrstalline Solid
Usage Used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor
Usage analgesic, norepinephrine uptake blocker, mu-opiod receptor agonist

Tadalafil is used to treat erectile dysfunction (ED, impotence; Inability to get or keep an erection), and the symptoms of benign prostatic hyperplasia (BPH; An enlarged prostate) which include difficulty urinating (hesitation, dribbling, weak stream, and incomplete bladder emptying), painful urination, and urinary frequency and urgency in adult men. Tadalafil (Adcirca) is used to improve the ability to exercise in people with pulmonary arterial hypertension (PAH; High blood pressure in the vessels carrying blood to the lungs, causing shortness of breath, dizziness, and tiredness). Tadalafil is in a class of medications called phosphodiesterase (PDE) inhibitors. It works to treat erectile dysfunction by increasing blood flow to the penis during sexual stimulation. This increased blood flow can cause an erection. Tadalafil treats PAH by relaxing the blood vessels in the lungs to allow blood to flow more easily.
If you are taking tadalafil to treat erectile dysfunction, you should know that it does not cure erectile dysfunction or increase sexual desire. Tadalafil does not prevent pregnancy or the spread of sexually transmitted diseases such as human immunodeficiency virus (HIV).
How should this medicine be used?
Tadalafil comes as a tablet to take by mouth. It may be taken with or without food.
If you are taking tadalafil to treat erectile dysfunction, follow your doctor's directions and the guidelines in this paragraph. There are two different ways to take tadalafil, either daily or on an as needed basis. Talk to your doctor about which dosing schedule is right for you. Tadalafil is sometimes taken as needed, usually at least 30 minutes before sexual activity and not more often than once every 24 hours. Your doctor will help you decide the best time for you to take tadalafil before sexual activity. Tadalafil is also sometimes taken once a day every day without regard to timing of sexual activity. You may attempt sexual activity at any time between doses. If you are taking tadalafil on a regular schedule, take it at around the same time every day. If you have certain health conditions or are taking certain medications, your doctor may tell you to take tadalafil less often or may prescribe a lower dose to be taken once a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take tadalafil exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Tadalafil Basic information
Drug for treatment of male erectile dysfunction disease Uses
Product Name: Tadalafil
Synonyms: TADALAFIL;IC 351;(6r,12ar)-6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione;TADALAFIL;Taladafil ;taladafil;(IC351)
CAS: 171596-29-5
MF: C22H19N3O4
MW: 389.4
EINECS: 200-835-2
Product Categories: Active Pharmaceutical Ingredients;Cnbio;Erectile Dysfunction;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Steroid and Hormone;Inhibitor;API;Tadalafil;NUCYNTA;Pyridines ,Halogenated Heterocycles
Mol File: 171596-29-5.mol
Tadalafil Chemical Properties
mp  298-300°C
storage temp.  Hygroscopic, -20?C Freezer, Under Inert Atmosphere
CAS DataBase Reference 171596-29-5(CAS DataBase Reference)
 
Safety Information
Hazard Codes  F,Xn
Risk Statements  11-20/21/22-36
Safety Statements  16-36/37
Hazardous Substances Data 171596-29-5(Hazardous Substances Data)
MSDS Information
 
Tadalafil Usage And Synthesis
Drug for treatment of male erectile dysfunction disease tadalafil, is an orally administrated drug developed by the pharmaceutical company Eli Lily for treatment of male erectile dysfunction disease. It belongs to the second generation of phosphodiesterase type 5 inhibitors. Study has shown that compared , the onset rate of tadalafil is very rapid with about 15 ~ 20 min for onset and with long-term effects up to 36h. Its T1/2 was 17.5h. In a study including 348 cases of patients with mild to severe erectile dysfunction, male patients were randomized for being subject to 20 mg of tadalafil or placebo. The results have showed that, compared with placebo, the intercourse success rate at 24 and 36 hours after taking the drug are both improved with most male patients can successfully have sexual intercourse for twice within 36 hours. There is also no difference in the incidence and severity of the adverse drug reactions compared with placebo. In the tadalafil group, more than 5% of men get headache and indigestion. 
[Adverse reactions] it has no serious adverse reactions. No adverse reactions such as facial flushing, vision abnormalities after serving have been observed. There has been occasionally headache and indigestion.
[Note] for patients serving nitrates, angina, heart disease, uncontrolled hypertension or hypotension. Patients who had got stroke within the past six months should be disabled.
The above information is edited by the chemicalbook of Dai Xiongfeng.
Uses It is a kind of PDE-5 inhibitors which can be used for the treatment of male erectile dysfunction. It is also the second generation of phosphodiesterase type 5 inhibitors used to treat male erectile dysfunction
Chemical Properties White to Off-White Cyrstalline Solid
Usage Used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor
Usage analgesic, norepinephrine uptake blocker, mu-opiod receptor agonist

Tadalafil is used to treat erectile dysfunction (ED, impotence; Inability to get or keep an erection), and the symptoms of benign prostatic hyperplasia (BPH; An enlarged prostate) which include difficulty urinating (hesitation, dribbling, weak stream, and incomplete bladder emptying), painful urination, and urinary frequency and urgency in adult men. Tadalafil (Adcirca) is used to improve the ability to exercise in people with pulmonary arterial hypertension (PAH; High blood pressure in the vessels carrying blood to the lungs, causing shortness of breath, dizziness, and tiredness). Tadalafil is in a class of medications called phosphodiesterase (PDE) inhibitors. It works to treat erectile dysfunction by increasing blood flow to the penis during sexual stimulation. This increased blood flow can cause an erection. Tadalafil treats PAH by relaxing the blood vessels in the lungs to allow blood to flow more easily.
If you are taking tadalafil to treat erectile dysfunction, you should know that it does not cure erectile dysfunction or increase sexual desire. Tadalafil does not prevent pregnancy or the spread of sexually transmitted diseases such as human immunodeficiency virus (HIV).
How should this medicine be used?
Tadalafil comes as a tablet to take by mouth. It may be taken with or without food.
If you are taking tadalafil to treat erectile dysfunction, follow your doctor's directions and the guidelines in this paragraph. There are two different ways to take tadalafil, either daily or on an as needed basis. Talk to your doctor about which dosing schedule is right for you. Tadalafil is sometimes taken as needed, usually at least 30 minutes before sexual activity and not more often than once every 24 hours. Your doctor will help you decide the best time for you to take tadalafil before sexual activity. Tadalafil is also sometimes taken once a day every day without regard to timing of sexual activity. You may attempt sexual activity at any time between doses. If you are taking tadalafil on a regular schedule, take it at around the same time every day. If you have certain health conditions or are taking certain medications, your doctor may tell you to take tadalafil less often or may prescribe a lower dose to be taken once a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take tadalafil exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

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